SDHB mutations are associated with response to temozolomide in patients with metastatic pheochromocytoma or paraganglioma. [electronic resource]
Producer: 20141125Description: 2711-20 p. digitalISSN:- 1097-0215
- Adrenal Gland Neoplasms -- drug therapy
- Adult
- Aged
- Aged, 80 and over
- Antineoplastic Agents, Alkylating -- therapeutic use
- Biomarkers, Tumor -- genetics
- Brain Neoplasms -- drug therapy
- DNA Methylation
- DNA Modification Methylases -- genetics
- DNA Repair Enzymes -- genetics
- Dacarbazine -- analogs & derivatives
- Female
- Follow-Up Studies
- Humans
- Male
- Middle Aged
- Mutation -- genetics
- Neoplasm Metastasis
- Neoplasm Staging
- Paraganglioma -- drug therapy
- Pheochromocytoma -- drug therapy
- Polymerase Chain Reaction
- Prognosis
- Promoter Regions, Genetic -- genetics
- Retrospective Studies
- Succinate Dehydrogenase -- genetics
- Survival Rate
- Temozolomide
- Tumor Suppressor Proteins -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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