RAC1 inhibition as a therapeutic target for gefitinib-resistant non-small-cell lung cancer. [electronic resource]
Producer: 20141020Description: 788-94 p. digitalISSN:- 1349-7006
- Aminoquinolines -- pharmacology
- Animals
- Antineoplastic Agents -- pharmacology
- Carcinoma, Non-Small-Cell Lung -- drug therapy
- Cell Line, Tumor -- drug effects
- Cell Movement -- genetics
- Drug Resistance, Neoplasm -- genetics
- ErbB Receptors -- antagonists & inhibitors
- Female
- Gefitinib
- Gene Silencing
- Humans
- Lung Neoplasms -- drug therapy
- Mice
- Mutation
- Protein Kinase Inhibitors -- pharmacology
- Pyrimidines -- pharmacology
- Quinazolines -- pharmacology
- Signal Transduction
- Xenograft Model Antitumor Assays
- rac1 GTP-Binding Protein -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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