Early-onset inflammatory bowel disease and common variable immunodeficiency-like disease caused by IL-21 deficiency. [electronic resource]
Producer: 20140718Description: 1651-9.e12 p. digitalISSN:- 1097-6825
- Age of Onset
- Amino Acid Sequence
- B-Lymphocyte Subsets -- immunology
- Child
- Child, Preschool
- Common Variable Immunodeficiency -- genetics
- Consanguinity
- DNA Mutational Analysis
- Female
- Humans
- Immunoglobulin Class Switching
- Immunoglobulin Isotypes -- blood
- Immunophenotyping
- Infant
- Inflammatory Bowel Diseases -- genetics
- Interleukins -- chemistry
- Lymphocyte Activation
- Male
- Models, Molecular
- Molecular Sequence Data
- Mutation
- Pedigree
- Protein Conformation
- Receptors, Interleukin-21 -- metabolism
- Sequence Alignment
- Signal Transduction
- Interleukin-21
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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