The novel thymidylate synthase inhibitor trifluorothymidine (TFT) and TRAIL synergistically eradicate non-small cell lung cancer cells. [electronic resource]
Producer: 20140918Description: 1273-83 p. digitalISSN:- 1432-0843
- Antimetabolites -- administration & dosage
- Antineoplastic Combined Chemotherapy Protocols -- pharmacology
- Apoptosis -- drug effects
- Carcinoma, Non-Small-Cell Lung -- drug therapy
- Caspases -- metabolism
- Cathepsin B -- metabolism
- Cell Cycle -- drug effects
- Cell Death -- drug effects
- Cell Line, Tumor
- Drug Synergism
- Humans
- Lung Neoplasms -- drug therapy
- RNA Interference
- RNA, Small Interfering -- metabolism
- TNF-Related Apoptosis-Inducing Ligand -- administration & dosage
- Thymidylate Synthase -- antagonists & inhibitors
- Trifluridine -- administration & dosage
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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