O-GlcNAcylation stabilizes β-catenin through direct competition with phosphorylation at threonine 41. [electronic resource]
Producer: 20141006Description: 3325-38 p. digitalISSN:- 1530-6860
- Acetylglucosamine -- metabolism
- Adenocarcinoma -- etiology
- Adherens Junctions -- metabolism
- Amino Acid Sequence
- Animals
- Colon -- metabolism
- Colorectal Neoplasms -- etiology
- Dietary Carbohydrates -- metabolism
- Enzyme Inhibitors -- pharmacology
- Glucose -- metabolism
- Glycosylation
- HEK293 Cells
- Humans
- Hyperglycemia -- complications
- Intestinal Mucosa -- metabolism
- MCF-7 Cells
- Male
- Mice
- Mice, Inbred C57BL
- Molecular Sequence Data
- N-Acetylglucosaminyltransferases -- antagonists & inhibitors
- Neoplasm Proteins -- chemistry
- Phosphorylation
- Protein Interaction Mapping
- Protein Processing, Post-Translational
- Protein Stability
- Proteolysis
- RNA, Small Interfering -- pharmacology
- Threonine -- chemistry
- Wnt Signaling Pathway
- alpha Catenin -- metabolism
- beta Catenin -- chemistry
- beta-N-Acetylhexosaminidases -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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