Lithocholic acid feeding results in direct hepato-toxicity independent of neutrophil function in mice. [electronic resource]
Producer: 20140707Description: 56-66 p. digitalISSN:- 1879-3169
- Animals
- Bile -- metabolism
- Bile Acids and Salts -- metabolism
- Blotting, Western
- Caspases -- metabolism
- Chemical and Drug Induced Liver Injury -- metabolism
- Cholestasis -- chemically induced
- Diet
- Hepatocytes -- drug effects
- Immunohistochemistry
- Inflammation -- genetics
- Lithocholic Acid -- metabolism
- Membrane Glycoproteins -- genetics
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- NADPH Oxidase 2
- NADPH Oxidases -- genetics
- Necrosis
- Neutrophils -- drug effects
- Real-Time Polymerase Chain Reaction
- Receptors, Immunologic -- genetics
- Up-Regulation -- drug effects
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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