Effectiveness of clopidogrel dose escalation to normalize active metabolite exposure and antiplatelet effects in CYP2C19 poor metabolizers. [electronic resource]
Producer: 20150409Description: 865-73 p. digitalISSN:- 1552-4604
- Adult
- Aged
- Amish -- genetics
- Area Under Curve
- Clopidogrel
- Cross-Over Studies
- Cytochrome P-450 CYP2C19 -- metabolism
- Female
- Genotype
- Humans
- Male
- Middle Aged
- Platelet Aggregation -- drug effects
- Platelet Aggregation Inhibitors -- administration & dosage
- Ticlopidine -- administration & dosage
- Young Adult
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Publication Type: Clinical Trial; Journal Article; Research Support, N.I.H., Extramural
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