Glucocorticoid sensitisation in Mixed Lineage Leukaemia-rearranged acute lymphoblastic leukaemia by the pan-BCL-2 family inhibitors gossypol and AT-101. [electronic resource]
Producer: 20140703Description: 1665-74 p. digitalISSN:- 1879-0852
- Antibiotics, Antineoplastic -- pharmacology
- Antineoplastic Agents, Phytogenic -- pharmacology
- Apoptosis -- genetics
- Dose-Response Relationship, Drug
- Drug Resistance, Neoplasm -- drug effects
- Gene Order -- genetics
- Glucocorticoids -- therapeutic use
- Gossypol -- analogs & derivatives
- Humans
- Infant
- Leukemia, Biphenotypic, Acute -- drug therapy
- Myeloid Cell Leukemia Sequence 1 Protein -- antagonists & inhibitors
- Precursor Cell Lymphoblastic Leukemia-Lymphoma -- drug therapy
- Prednisolone -- therapeutic use
- Proto-Oncogene Proteins c-bcl-2 -- metabolism
- Sirolimus -- pharmacology
- Tumor Cells, Cultured
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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