CDK5-mediated phosphorylation of p19INK4d avoids DNA damage-induced neurodegeneration in mouse hippocampus and prevents loss of cognitive functions. [electronic resource]
Producer: 20140630Description: 1309-24 p. digitalISSN:- 0006-3002
- Amyloid beta-Peptides -- pharmacology
- Animals
- Apoptosis
- Calcium -- metabolism
- Cell Line, Tumor
- Cell Survival
- Cognition -- physiology
- Cyclin-Dependent Kinase 5 -- genetics
- Cyclin-Dependent Kinase Inhibitor p19 -- genetics
- Cytotoxins -- pharmacology
- DNA Damage
- DNA Repair -- genetics
- Feedback, Physiological
- Gene Expression Regulation
- Hippocampus -- cytology
- Humans
- Mice
- Neurons -- cytology
- Peptide Fragments -- pharmacology
- Phosphorylation -- drug effects
- Primary Cell Culture
- Signal Transduction
- Transcription, Genetic
- Zinostatin -- pharmacology
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Publication Type: Journal Article
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