Blockade of Jagged/Notch pathway abrogates transforming growth factor β2-induced epithelial-mesenchymal transition in human retinal pigment epithelium cells. [electronic resource]
Producer: 20141228Description: 523-34 p. digitalISSN:- 1875-5666
- Amyloid Precursor Protein Secretases -- antagonists & inhibitors
- Calcium-Binding Proteins -- genetics
- Epithelial Cells -- drug effects
- Epithelial-Mesenchymal Transition -- drug effects
- Gene Expression Regulation
- Homeodomain Proteins -- genetics
- Humans
- Intercellular Signaling Peptides and Proteins -- genetics
- Jagged-1 Protein
- Membrane Proteins -- genetics
- Mitogen-Activated Protein Kinases -- metabolism
- Phosphatidylinositol 3-Kinases
- Proto-Oncogene Proteins c-akt -- metabolism
- RNA Interference
- RNA, Small Interfering -- genetics
- Receptors, Notch -- metabolism
- Retinal Pigment Epithelium -- drug effects
- Serrate-Jagged Proteins
- Signal Transduction -- drug effects
- Smad Proteins -- metabolism
- Snail Family Transcription Factors
- Transcription Factors -- genetics
- Transforming Growth Factor beta2 -- metabolism
- Zinc Finger E-box-Binding Homeobox 1
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Review
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