Synergistic inhibition of HCC and liver cancer stem cell proliferation by targeting RAS/RAF/MAPK and WNT/β-catenin pathways. [electronic resource]
Producer: 20140615Description: 1709-13 p. digitalISSN:- 1791-7530
- Animals
- Antineoplastic Agents -- pharmacology
- Carcinoma, Hepatocellular -- metabolism
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Cell Transformation, Neoplastic -- metabolism
- Disease Models, Animal
- Drug Synergism
- Female
- Humans
- Immunophenotyping
- Inhibitor of Apoptosis Proteins -- metabolism
- Liver Neoplasms -- metabolism
- Mice
- Mitogen-Activated Protein Kinases -- metabolism
- Neoplastic Stem Cells -- drug effects
- Niacinamide -- analogs & derivatives
- Phenotype
- Phenylurea Compounds -- pharmacology
- Poly(ADP-ribose) Polymerases -- metabolism
- Protein Kinase Inhibitors -- pharmacology
- Proto-Oncogene Proteins c-bcl-2 -- metabolism
- Proto-Oncogene Proteins p21(ras) -- metabolism
- Signal Transduction -- drug effects
- Sorafenib
- Sulfonamides -- pharmacology
- Survivin
- Wnt Signaling Pathway -- drug effects
- raf Kinases -- metabolism
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Publication Type: Journal Article
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