Expression of cereblon protein assessed by immunohistochemicalstaining in myeloma cells is associated with superior response of thalidomide- and lenalidomide-based treatment, but not bortezomib-based treatment, in patients with multiple myeloma. [electronic resource]
Producer: 20140912Description: 1371-80 p. digitalISSN:- 1432-0584
- Adaptor Proteins, Signal Transducing
- Aged
- Angiogenesis Inhibitors -- administration & dosage
- Antineoplastic Combined Chemotherapy Protocols -- therapeutic use
- Bone Marrow Examination -- methods
- Boronic Acids -- administration & dosage
- Bortezomib
- Dexamethasone -- administration & dosage
- Female
- Follow-Up Studies
- Gene Expression Profiling
- Humans
- Lenalidomide
- Male
- Melphalan -- administration & dosage
- Middle Aged
- Multiple Myeloma -- drug therapy
- Neoplasm Proteins -- analysis
- Neoplastic Stem Cells -- chemistry
- Paraffin Embedding
- Peptide Hydrolases -- analysis
- Prednisolone -- administration & dosage
- Pyrazines -- administration & dosage
- Salvage Therapy
- Survival Analysis
- Syndecan-1 -- analysis
- Thalidomide -- administration & dosage
- Treatment Outcome
- Ubiquitin-Protein Ligases
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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