Clofarabine in combination with a standard remission induction regimen (cytosine arabinoside and idarubicin) in patients with previously untreated intermediate and bad-risk acute myelogenous leukemia (AML) or high-risk myelodysplastic syndrome (HR-MDS): phase I results of an ongoing phase I/II study of the leukemia groups of EORTC and GIMEMA (EORTC GIMEMA 06061/AML-14A trial). [electronic resource]
Producer: 20140623Description: 965-75 p. digitalISSN:- 1432-0584
- Adenine Nucleotides -- administration & dosage
- Adult
- Aged
- Antineoplastic Combined Chemotherapy Protocols -- administration & dosage
- Arabinonucleosides -- administration & dosage
- Clofarabine
- Consolidation Chemotherapy
- Cytarabine -- administration & dosage
- Fatigue -- chemically induced
- Female
- Gastrointestinal Diseases -- chemically induced
- Humans
- Hydroxyurea -- therapeutic use
- Hyperbilirubinemia -- chemically induced
- Idarubicin -- administration & dosage
- Leukemia, Myeloid, Acute -- drug therapy
- Male
- Middle Aged
- Myelodysplastic Syndromes -- drug therapy
- Remission Induction
- Risk
- Treatment Outcome
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Publication Type: Clinical Trial, Phase I; Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
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