DMBA/TPA treatment is necessary for BCC formation from patched deficient epidermal cells in Ptch(flox/flox)CD4Cre(+/-) mice. [electronic resource]
Producer: 20150113Description: 2620-2629 p. digitalISSN:- 1523-1747
- 9,10-Dimethyl-1,2-benzanthracene -- adverse effects
- Alleles
- Animals
- CD4-Positive T-Lymphocytes -- pathology
- Carcinogenesis -- chemically induced
- Carcinogens -- pharmacology
- Carcinoma, Basal Cell -- chemically induced
- Disease Models, Animal
- Epidermis -- pathology
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Mice, Transgenic
- Mutation -- genetics
- Patched Receptors
- Patched-1 Receptor
- Proto-Oncogene Proteins p21(ras) -- genetics
- Receptors, Cell Surface -- deficiency
- Signal Transduction -- physiology
- Skin Neoplasms -- chemically induced
- Stem Cells -- pathology
- Tetradecanoylphorbol Acetate -- adverse effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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