Disturbed flow promotes endothelial senescence via a p53-dependent pathway. [electronic resource]
Producer: 20140620Description: 985-95 p. digitalISSN:- 1524-4636
- Animals
- Aortic Diseases -- genetics
- Atherosclerosis -- genetics
- Bioreactors
- Cell Movement
- Cells, Cultured
- Cellular Senescence -- drug effects
- Cyclin-Dependent Kinase Inhibitor p21 -- genetics
- Diet, High-Fat
- Disease Models, Animal
- Endothelial Cells -- drug effects
- Enzyme Activation
- Enzyme Activators -- pharmacology
- Human Umbilical Vein Endothelial Cells -- metabolism
- Humans
- Mechanotransduction, Cellular -- drug effects
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- RNA Interference
- Receptors, LDL -- deficiency
- Regional Blood Flow
- Sirtuin 1 -- metabolism
- Stress, Mechanical
- Swine
- Time Factors
- Transfection
- Tumor Suppressor Protein p53 -- genetics
- Wound Healing
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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