Intracellular glutathione depletion by oridonin leads to apoptosis in hepatic stellate cells. [electronic resource]
Producer: 20141028Description: 3327-44 p. digitalISSN:- 1420-3049
- Animals
- Apoptosis -- drug effects
- Caspase 3 -- metabolism
- Cell Line
- Cell Survival -- drug effects
- Diterpenes, Kaurane -- pharmacology
- Enzyme Activation -- drug effects
- Glutathione -- metabolism
- Hepatic Stellate Cells -- drug effects
- Inhibitory Concentration 50
- Intracellular Space -- metabolism
- Membrane Potential, Mitochondrial -- drug effects
- Mitogen-Activated Protein Kinases -- metabolism
- Oxidative Stress
- Phosphorylation
- Rats
- Reactive Oxygen Species -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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