Glabridin inhibits migration and invasion by transcriptional inhibition of matrix metalloproteinase 9 through modulation of NF-κB and AP-1 activity in human liver cancer cells. [electronic resource]
Producer: 20150119Description: 3037-50 p. digitalISSN:- 1476-5381
- Animals
- Antineoplastic Agents, Phytogenic -- pharmacology
- Carcinoma, Hepatocellular -- drug therapy
- Cell Line, Tumor
- Cell Movement -- drug effects
- Cell Survival -- drug effects
- Dose-Response Relationship, Drug
- Extracellular Signal-Regulated MAP Kinases -- metabolism
- Humans
- Isoflavones -- pharmacology
- JNK Mitogen-Activated Protein Kinases -- metabolism
- Liver Neoplasms -- drug therapy
- Male
- Matrix Metalloproteinase 9 -- genetics
- Mice, Inbred BALB C
- Mice, Nude
- NF-kappa B -- metabolism
- Neoplasm Invasiveness
- Phenols -- pharmacology
- Phosphorylation
- Signal Transduction -- drug effects
- Time Factors
- Tissue Inhibitor of Metalloproteinase-1 -- metabolism
- Transcription Factor AP-1 -- metabolism
- Transcription, Genetic -- drug effects
- Transfection
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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