Profound prevention of experimental brain metastases of breast cancer by temozolomide in an MGMT-dependent manner. [electronic resource]
Producer: 20150209Description: 2727-39 p. digitalISSN:- 1557-3265
- Animals
- Antineoplastic Agents, Alkylating -- pharmacology
- Brain Neoplasms -- metabolism
- Breast Neoplasms -- drug therapy
- Cell Line, Tumor
- DNA Modification Methylases -- genetics
- DNA Repair Enzymes -- genetics
- Dacarbazine -- analogs & derivatives
- Dose-Response Relationship, Drug
- Drug Administration Schedule
- Female
- Humans
- Immunohistochemistry
- Kaplan-Meier Estimate
- MCF-7 Cells
- Mice
- Mice, Nude
- RNA Interference
- Temozolomide
- Treatment Outcome
- Triple Negative Breast Neoplasms -- drug therapy
- Tumor Suppressor Proteins -- genetics
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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