Increased resistance to malaria in mice with methylenetetrahydrofolate reductase (Mthfr) deficiency suggests a mechanism for selection of the MTHFR 677C>T (c.665C>T) variant. [electronic resource]
Producer: 20141212Description: 594-600 p. digitalISSN:- 1098-1004
- Animals
- Brain -- metabolism
- Folic Acid -- genetics
- Homocystinuria -- genetics
- Humans
- Interferon-gamma -- biosynthesis
- Interleukin-10 -- biosynthesis
- Malaria, Cerebral -- etiology
- Methylenetetrahydrofolate Reductase (NADPH2) -- deficiency
- Mice
- Muscle Spasticity -- genetics
- Plasmodium -- metabolism
- Polymorphism, Single Nucleotide
- Psychotic Disorders -- genetics
- Selection, Genetic -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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