Cyclic marinopyrrole derivatives as disruptors of Mcl-1 and Bcl-x(L) binding to Bim. [electronic resource]
Producer: 20141112Description: 1335-48 p. digitalISSN:- 1660-3397
- Apoptosis -- drug effects
- Apoptosis Regulatory Proteins -- chemistry
- Bcl-2-Like Protein 11
- Blotting, Western
- Breast Neoplasms -- drug therapy
- Catalysis
- Cell Line, Tumor
- Drug Screening Assays, Antitumor
- Enzyme-Linked Immunosorbent Assay
- Female
- Humans
- Indicators and Reagents
- Isomerism
- Magnetic Resonance Spectroscopy
- Marine Toxins -- pharmacology
- Membrane Proteins -- chemistry
- Myeloid Cell Leukemia Sequence 1 Protein -- metabolism
- Protein Binding -- drug effects
- Proto-Oncogene Proteins -- chemistry
- Pyrroles -- chemical synthesis
- Spectrophotometry, Ultraviolet
- Structure-Activity Relationship
- bcl-X Protein -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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