A novel blood-brain barrier co-culture system for drug targeting of Alzheimer's disease: establishment by using acitretin as a model drug. [electronic resource]
Producer: 20150212Description: e91003 p. digitalISSN:- 1932-6203
- ADAM Proteins -- genetics
- ADAM10 Protein
- Acitretin -- metabolism
- Alzheimer Disease -- drug therapy
- Amyloid Precursor Protein Secretases -- genetics
- Amyloid beta-Protein Precursor -- genetics
- Animals
- Biological Assay
- Biological Transport
- Blood-Brain Barrier -- drug effects
- Brain -- cytology
- Cell Line, Tumor
- Coculture Techniques
- Drug Delivery Systems
- Endothelial Cells -- cytology
- Endothelium, Vascular -- cytology
- Gene Expression -- drug effects
- Genes, Reporter
- Humans
- Keratolytic Agents -- metabolism
- Luciferases -- genetics
- Membrane Proteins -- genetics
- Models, Biological
- Neurons -- cytology
- Promoter Regions, Genetic
- Recombinant Fusion Proteins -- genetics
- Swine
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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