Increased 14-3-3ζ expression in the multidrug-resistant leukemia cell line HL-60/VCR as compared to the parental line mediates cell growth and apoptosis in part through modification of gene expression. [electronic resource]
Producer: 20140819Description: 177-86 p. digitalISSN:- 1421-9662
- 14-3-3 Proteins -- antagonists & inhibitors
- ATP Binding Cassette Transporter, Subfamily B
- ATP Binding Cassette Transporter, Subfamily B, Member 1 -- biosynthesis
- Antineoplastic Agents, Phytogenic -- pharmacology
- Apoptosis -- drug effects
- Cell Cycle -- drug effects
- Drug Resistance, Multiple -- genetics
- Drug Resistance, Neoplasm -- genetics
- Gene Expression Profiling
- Gene Expression Regulation, Leukemic
- HL-60 Cells -- drug effects
- Humans
- Myeloid Cell Leukemia Sequence 1 Protein -- biosynthesis
- Neoplasm Proteins -- antagonists & inhibitors
- Oligonucleotide Array Sequence Analysis
- Proto-Oncogene Proteins c-bcl-2 -- biosynthesis
- RNA Interference
- RNA, Messenger -- biosynthesis
- RNA, Neoplasm -- biosynthesis
- RNA, Small Interfering -- pharmacology
- Subcellular Fractions -- metabolism
- Topoisomerase I Inhibitors -- pharmacology
- Topotecan -- pharmacology
- Vincristine -- pharmacology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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