(5-Hydroxy-4-oxo-4H-pyran-2-yl)methyl 6-hydroxynaphthalene-2-carboxylate, a kojic acid derivative, inhibits inflammatory mediator production via the suppression of Syk/Src and NF-κB activation. [electronic resource]
Producer: 20141228Description: 37-45 p. digitalISSN:- 1878-1705
- Animals
- Anti-Inflammatory Agents -- pharmacology
- Cell Line
- Cell Survival -- drug effects
- Cyclooxygenase 2 -- genetics
- Dinoprostone -- metabolism
- Ethanol
- Gastritis -- chemically induced
- HEK293 Cells
- Humans
- Hydrochloric Acid
- I-kappa B Proteins -- immunology
- Intracellular Signaling Peptides and Proteins -- antagonists & inhibitors
- Male
- Mice, Inbred ICR
- NF-KappaB Inhibitor alpha
- NF-kappa B -- antagonists & inhibitors
- Naphthols -- pharmacology
- Nitric Oxide -- metabolism
- Nitric Oxide Synthase Type II -- genetics
- Protein-Tyrosine Kinases -- antagonists & inhibitors
- Pyrones -- chemistry
- Stomach -- drug effects
- Syk Kinase
- src-Family Kinases -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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