tPA promotes ADAMTS-4-induced CSPG degradation, thereby enhancing neuroplasticity following spinal cord injury. [electronic resource]
Producer: 20140924Description: 28-42 p. digitalISSN:- 1095-953X
- ADAM Proteins -- metabolism
- ADAMTS4 Protein
- Animals
- Axons -- drug effects
- Cells, Cultured
- Chondroitin Sulfate Proteoglycans -- metabolism
- Female
- Neurites -- drug effects
- Neurocan
- Neuronal Plasticity -- drug effects
- Neuropeptides -- pharmacology
- Neuroprotective Agents -- pharmacology
- Plasminogen Activator Inhibitor 1 -- pharmacology
- Procollagen N-Endopeptidase -- metabolism
- Rats
- Rats, Wistar
- Recovery of Function
- Serine Proteinase Inhibitors -- pharmacology
- Serpins -- pharmacology
- Spinal Cord -- drug effects
- Spinal Cord Compression -- drug therapy
- Spinal Cord Injuries -- drug therapy
- Tissue Plasminogen Activator -- antagonists & inhibitors
- Neuroserpin
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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