hnRNP M facilitates exon 7 inclusion of SMN2 pre-mRNA in spinal muscular atrophy by targeting an enhancer on exon 7. [electronic resource]
Producer: 20140613Description: 306-15 p. digitalISSN:- 0006-3002
- Anterior Horn Cells -- metabolism
- Cell Culture Techniques
- Enhancer Elements, Genetic -- genetics
- Exons -- genetics
- Gene Expression Regulation
- Heterogeneous-Nuclear Ribonucleoprotein Group M -- genetics
- Molecular Targeted Therapy
- Motor Neurons -- metabolism
- Muscular Atrophy, Spinal -- etiology
- Nerve Tissue Proteins -- metabolism
- Nuclear Proteins -- metabolism
- RNA Precursors -- metabolism
- RNA-Binding Proteins -- metabolism
- Ribonucleoproteins -- metabolism
- Serine-Arginine Splicing Factors
- Spinal Cord -- metabolism
- Splicing Factor U2AF
- Survival of Motor Neuron 1 Protein -- metabolism
- Survival of Motor Neuron 2 Protein -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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