Synergistic targeting of AML stem/progenitor cells with IAP antagonist birinapant and demethylating agents. [electronic resource]
Producer: 20140331Description: djt440 p. digitalISSN:- 1460-2105
- Adult
- Aged
- Antimetabolites, Antineoplastic -- administration & dosage
- Antineoplastic Combined Chemotherapy Protocols -- pharmacology
- Apoptosis Regulatory Proteins
- Azacitidine -- administration & dosage
- Blotting, Western
- Caspase 8 -- metabolism
- DNA Methylation -- drug effects
- Dipeptides -- administration & dosage
- Drug Synergism
- Female
- Gene Expression Regulation, Neoplastic
- Humans
- Indoles -- administration & dosage
- Inhibitor of Apoptosis Proteins -- antagonists & inhibitors
- Intracellular Signaling Peptides and Proteins -- agonists
- Leukemia, Myeloid, Acute -- drug therapy
- Male
- Middle Aged
- Mitochondrial Proteins -- agonists
- Neoplastic Stem Cells
- Protein Array Analysis
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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