Towards effective and safe thrombolysis and thromboprophylaxis: preclinical testing of a novel antibody-targeted recombinant plasminogen activator directed against activated platelets. [electronic resource]
Producer: 20140616Description: 1083-93 p. digitalISSN:- 1524-4571
- Animals
- Blood Platelets -- drug effects
- CHO Cells
- Carotid Arteries -- diagnostic imaging
- Cricetinae
- Cricetulus
- Drug Evaluation, Preclinical
- Fibrinolytic Agents -- adverse effects
- Integrin alpha2 -- immunology
- Mice
- Mice, Inbred C57BL
- Plasminogen -- metabolism
- Platelet Activation
- Recombinant Fusion Proteins -- genetics
- Single-Chain Antibodies -- genetics
- Thromboembolism -- drug therapy
- Thrombolytic Therapy
- Ultrasonography
- Urokinase-Type Plasminogen Activator -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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