Nickel nanoparticles cause exaggerated lung and airway remodeling in mice lacking the T-box transcription factor, TBX21 (T-bet). [electronic resource]
Producer: 20140908Description: 7 p. digitalISSN:- 1743-8977
- Airway Remodeling -- drug effects
- Animals
- Antibodies, Blocking -- pharmacology
- Antibodies, Monoclonal -- pharmacology
- Bronchoalveolar Lavage Fluid -- cytology
- Chemokine CCL2 -- antagonists & inhibitors
- Collagen -- metabolism
- Enzyme-Linked Immunosorbent Assay
- Fibrosis -- pathology
- Lung -- pathology
- Lung Diseases -- chemically induced
- Male
- Metal Nanoparticles -- toxicity
- Metaplasia -- pathology
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Mucin 5AC -- genetics
- Mucin-5B -- genetics
- Nickel -- toxicity
- Pulmonary Eosinophilia -- pathology
- Pulmonary Fibrosis -- chemically induced
- Real-Time Polymerase Chain Reaction
- T-Box Domain Proteins -- genetics
- T-bet Transcription Factor
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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