Pharmacogenetic-based efavirenz dose modification: suggestions for an African population and the different CYP2B6 genotypes. [electronic resource]
Producer: 20141028Description: e86919 p. digitalISSN:- 1932-6203
- ATP Binding Cassette Transporter, Subfamily B
- ATP Binding Cassette Transporter, Subfamily B, Member 1 -- genetics
- Adult
- Alkynes
- Area Under Curve
- Aryl Hydrocarbon Hydroxylases -- genetics
- Benzoxazines -- pharmacokinetics
- Cyclopropanes
- Cytochrome P-450 CYP2B6
- Cytochrome P-450 CYP3A -- genetics
- Dose-Response Relationship, Drug
- Drug Therapy, Combination
- Female
- Genotype
- HIV Infections -- drug therapy
- Humans
- Lamivudine -- therapeutic use
- Male
- Middle Aged
- Mutation
- Pharmacogenetics
- Reverse Transcriptase Inhibitors -- pharmacokinetics
- Treatment Outcome
- Uganda
- Zidovudine -- therapeutic use
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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