The thiocarbamate disulphide drug, disulfiram induces osteopenia in rats by inhibition of osteoblast function due to suppression of acetaldehyde dehydrogenase activity. [electronic resource]
Producer: 20141228Description: 257-70 p. digitalISSN:- 1096-0929
- Aldehyde Dehydrogenase -- antagonists & inhibitors
- Animals
- Apoptosis -- drug effects
- Base Sequence
- Bone Diseases, Metabolic -- chemically induced
- Cell Proliferation -- drug effects
- Cells, Cultured
- DNA Primers
- Disulfiram -- toxicity
- Glutathione -- metabolism
- Osteoblasts -- cytology
- Rats
- Real-Time Polymerase Chain Reaction
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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