Critical role for the AIM2 inflammasome during acute CNS bacterial infection. [electronic resource]
Producer: 20140615Description: 704-11 p. digitalISSN:- 1471-4159
- Animals
- Apoptosis Regulatory Proteins
- Brain Abscess -- immunology
- CARD Signaling Adaptor Proteins
- Carrier Proteins -- genetics
- Caspase 1 -- deficiency
- Caspases -- deficiency
- Caspases, Initiator
- Cytokines -- metabolism
- Cytoskeletal Proteins -- deficiency
- DNA, Bacterial -- immunology
- DNA-Binding Proteins
- Disease Susceptibility
- Female
- Immunity, Innate
- Inflammasomes -- physiology
- Inflammation Mediators -- physiology
- Interleukin-1beta -- metabolism
- Male
- Methicillin-Resistant Staphylococcus aureus -- immunology
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Microglia -- metabolism
- Models, Immunological
- NLR Family, Pyrin Domain-Containing 3 Protein
- Nuclear Proteins -- deficiency
- Phenotype
- Staphylococcal Infections -- immunology
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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