Lysosomal-mediated waste clearance in retinal pigment epithelial cells is regulated by CRYBA1/βA3/A1-crystallin via V-ATPase-MTORC1 signaling. [electronic resource]
Producer: 20150330Description: 480-96 p. digitalISSN:- 1554-8635
- Animals
- Autophagy -- genetics
- Crystallins -- genetics
- Lysosomes -- metabolism
- Mechanistic Target of Rapamycin Complex 1
- Mice
- Mice, Knockout
- Multiprotein Complexes -- genetics
- Phagocytosis -- physiology
- Phagosomes -- metabolism
- Rats
- Retinal Pigment Epithelium -- cytology
- Signal Transduction -- physiology
- TOR Serine-Threonine Kinases -- genetics
- Vacuolar Proton-Translocating ATPases -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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