Histone deacetylase inhibitors selectively target homology dependent DNA repair defective cells and elevate non-homologous endjoining activity. [electronic resource]
Producer: 20140929Description: e87203 p. digitalISSN:- 1932-6203
- Animals
- Antigens, Nuclear -- genetics
- B-Lymphocytes -- cytology
- Blotting, Western
- Cell Survival -- drug effects
- Cells, Cultured
- Chickens
- DNA Damage -- drug effects
- DNA End-Joining Repair -- drug effects
- DNA Repair -- drug effects
- DNA-Binding Proteins -- antagonists & inhibitors
- Electrophoresis, Gel, Pulsed-Field
- Fluorescent Antibody Technique
- Histone Deacetylase Inhibitors -- pharmacology
- Humans
- Hydroxamic Acids -- pharmacology
- Ku Autoantigen
- Luciferases -- metabolism
- Mutation -- genetics
- Neoplasms -- drug therapy
- RNA, Small Interfering -- genetics
- Rad51 Recombinase -- antagonists & inhibitors
- RecQ Helicases -- genetics
- Vorinostat
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
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