A nonsense mutation in mouse Tardbp affects TDP43 alternative splicing activity and causes limb-clasping and body tone defects. [electronic resource]
Producer: 20141029Description: e85962 p. digitalISSN:- 1932-6203
- Adaptor Proteins, Vesicular Transport -- metabolism
- Alternative Splicing -- genetics
- Amyotrophic Lateral Sclerosis -- genetics
- Animals
- Behavior, Animal
- Body Weight
- Codon, Nonsense -- genetics
- DNA-Binding Proteins -- genetics
- Embryo Loss -- genetics
- Ethylnitrosourea
- Hand Strength
- Hindlimb -- metabolism
- Homozygote
- Male
- Mice
- Mice, Inbred C57BL
- Mice, Transgenic
- Motor Activity
- Mutant Proteins -- genetics
- Phenotype
- Point Mutation -- genetics
- RNA, Messenger -- genetics
- Superoxide Dismutase
- Superoxide Dismutase-1
No physical items for this record
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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