The effect of ABCG2 and ABCC4 on the pharmacokinetics of methotrexate in the brain. [electronic resource]
Producer: 20141028Description: 537-40 p. digitalISSN:- 1521-009X
- ATP Binding Cassette Transporter, Subfamily G, Member 2
- ATP-Binding Cassette Transporters -- genetics
- Animals
- Antimetabolites, Antineoplastic -- blood
- Area Under Curve
- Biological Transport
- Blood-Brain Barrier -- metabolism
- Brain -- metabolism
- Brain Neoplasms -- metabolism
- Chromatography, High Pressure Liquid
- Gene Knockout Techniques
- Methotrexate -- blood
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Microdialysis
- Multidrug Resistance-Associated Proteins -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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