A systems toxicology approach identifies Lyn as a key signaling phosphoprotein modulated by mercury in a B lymphocyte cell model. [electronic resource]
Producer: 20140516Description: 47-54 p. digitalISSN:- 1096-0333
- Animals
- Autoimmune Diseases -- chemically induced
- B-Lymphocytes -- drug effects
- Biomarkers -- metabolism
- Cell Line
- Chromatography, High Pressure Liquid
- Mercury -- toxicity
- Mercury Poisoning -- enzymology
- Mice
- Osmolar Concentration
- Peptide Fragments -- agonists
- Phosphorylation -- drug effects
- Protein Processing, Post-Translational -- drug effects
- Protein Tyrosine Phosphatases -- pharmacology
- Receptors, Antigen, B-Cell -- agonists
- Signal Transduction -- drug effects
- Tandem Mass Spectrometry
- Tyrosine -- metabolism
- Vanadates -- pharmacology
- src-Family Kinases -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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