BIMEL is a key effector molecule in oxidative stress-mediated apoptosis in acute myeloid leukemia cells when combined with arsenic trioxide and buthionine sulfoximine. [electronic resource]
Producer: 20141030Description: 27 p. digitalISSN:- 1471-2407
- Apoptosis -- drug effects
- Apoptosis Regulatory Proteins -- deficiency
- Arsenic Trioxide
- Arsenicals -- administration & dosage
- Bcl-2-Like Protein 11
- Buthionine Sulfoximine -- administration & dosage
- Drug Combinations
- Gene Knockdown Techniques -- methods
- HL-60 Cells
- Humans
- Leukemia, Myeloid, Acute -- metabolism
- Membrane Proteins -- deficiency
- Oxidative Stress -- drug effects
- Oxides -- administration & dosage
- Phosphorylation -- drug effects
- Proto-Oncogene Proteins -- deficiency
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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