Saikosaponin-D enhances radiosensitivity of hepatoma cells under hypoxic conditions by inhibiting hypoxia-inducible factor-1α. [electronic resource]
Producer: 20160718Description: 37-51 p. digitalISSN:- 1421-9778
- Animals
- Apoptosis -- drug effects
- Carcinoma, Hepatocellular -- metabolism
- Cell Hypoxia -- drug effects
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Cell Survival -- drug effects
- Humans
- Hypoxia-Inducible Factor 1, alpha Subunit -- antagonists & inhibitors
- Liver Neoplasms -- metabolism
- Male
- Mice, Inbred BALB C
- Mice, Nude
- Oleanolic Acid -- analogs & derivatives
- Radiation Tolerance -- drug effects
- Saponins -- chemistry
- Tumor Stem Cell Assay
- Tumor Suppressor Protein p53 -- metabolism
- Vascular Endothelial Growth Factor A -- metabolism
- Xenograft Model Antitumor Assays
- bcl-2-Associated X Protein -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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