Sarsasapogenin induces apoptosis via the reactive oxygen species-mediated mitochondrial pathway and ER stress pathway in HeLa cells. [electronic resource]
Producer: 20140117Description: 519-24 p. digitalISSN:- 1090-2104
- Anemarrhena -- chemistry
- Antineoplastic Agents -- pharmacology
- Cell Cycle Checkpoints
- Cinnamates -- pharmacology
- Cytochromes c -- biosynthesis
- Drugs, Chinese Herbal -- pharmacology
- Endoplasmic Reticulum Stress -- drug effects
- Female
- G1 Phase Cell Cycle Checkpoints -- drug effects
- HeLa Cells
- Humans
- M Phase Cell Cycle Checkpoints -- drug effects
- Mitochondria -- drug effects
- Mitochondrial Membranes -- drug effects
- Reactive Oxygen Species -- metabolism
- Spirostans -- pharmacology
- Thiourea -- analogs & derivatives
- Transcription Factor CHOP -- biosynthesis
- Unfolded Protein Response
- Uterine Cervical Neoplasms -- metabolism
- bcl-2-Associated X Protein -- biosynthesis
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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