Norcantharidin induced DU145 cell apoptosis through ROS-mediated mitochondrial dysfunction and energy depletion. [electronic resource]
Producer: 20140728Description: e84610 p. digitalISSN:- 1932-6203
- AMP-Activated Protein Kinases
- Adenosine Triphosphate -- metabolism
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Bisbenzimidazole
- Blotting, Western
- Bridged Bicyclo Compounds, Heterocyclic -- pharmacology
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Cytochromes c -- metabolism
- Dose-Response Relationship, Drug
- Flow Cytometry
- Humans
- In Situ Nick-End Labeling
- Male
- Membrane Potential, Mitochondrial -- drug effects
- Micronucleus Tests
- Mitochondria -- drug effects
- Proliferating Cell Nuclear Antigen -- metabolism
- Prostatic Neoplasms -- drug therapy
- Reactive Oxygen Species -- metabolism
- Superoxide Dismutase -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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