The apoptosis repressor with a CARD domain (ARC) gene is a direct hypoxia-inducible factor 1 target gene and promotes survival and proliferation of VHL-deficient renal cancer cells. [electronic resource]
Producer: 20140319Description: 739-51 p. digitalISSN:- 1098-5549
- AIDS-Related Complex -- genetics
- Animals
- Apoptosis -- genetics
- Carcinoma, Renal Cell -- genetics
- Cell Hypoxia -- genetics
- Cell Proliferation
- Cell Survival
- Cells, Cultured
- Gene Expression Regulation, Neoplastic -- genetics
- Humans
- Hypoxia-Inducible Factor 1, alpha Subunit -- genetics
- Kidney Neoplasms -- genetics
- Mice
- Transcription Factors -- genetics
- Tumor Suppressor Proteins -- genetics
- Von Hippel-Lindau Tumor Suppressor Protein -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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