FTY720 (s)-phosphonate preserves sphingosine 1-phosphate receptor 1 expression and exhibits superior barrier protection to FTY720 in acute lung injury. [electronic resource]
Producer: 20140422Description: e189-99 p. digitalISSN:- 1530-0293
- Acute Lung Injury -- drug therapy
- Animals
- Arrestins -- drug effects
- Bleomycin -- pharmacology
- Blotting, Western
- Capillary Permeability -- drug effects
- Cells, Cultured
- Disease Models, Animal
- Endothelial Cells -- drug effects
- Fingolimod Hydrochloride
- Fluorescent Antibody Technique
- Humans
- Mice
- Mice, Inbred C57BL
- Propylene Glycols -- pharmacology
- Random Allocation
- Receptors, G-Protein-Coupled -- drug effects
- Receptors, Lysosphingolipid -- drug effects
- Sensitivity and Specificity
- Sphingosine -- analogs & derivatives
- beta-Arrestins
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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