Colon cancer cells escape 5FU chemotherapy-induced cell death by entering stemness and quiescence associated with the c-Yes/YAP axis. [electronic resource]
Producer: 20141014Description: 837-46 p. digitalISSN:- 1557-3265
- Antimetabolites, Antineoplastic -- pharmacology
- Biomarkers, Tumor -- metabolism
- Cell Cycle Checkpoints
- Cell Cycle Proteins
- Cell Nucleus -- metabolism
- Cell Proliferation
- Checkpoint Kinase 2 -- metabolism
- Chemotherapy, Adjuvant
- Colonic Neoplasms -- drug therapy
- Disease-Free Survival
- Drug Resistance, Neoplasm
- Fluorouracil -- pharmacology
- Gene Expression
- HT29 Cells
- Humans
- Kaplan-Meier Estimate
- Liver Neoplasms -- drug therapy
- Neoadjuvant Therapy
- Neoplasm Micrometastasis -- prevention & control
- Neoplastic Stem Cells -- drug effects
- Nuclear Proteins -- genetics
- Proportional Hazards Models
- Protein Transport
- Proto-Oncogene Proteins c-yes -- genetics
- Transcription Factors -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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