Deletion of Mecom in mouse results in early-onset spinal deformity and osteopenia. [electronic resource]
Producer: 20141021Description: 148-61 p. digitalISSN:- 1873-2763
- Animals
- Biomechanical Phenomena
- Bone Diseases, Metabolic -- complications
- Collagen -- genetics
- DNA-Binding Proteins -- metabolism
- Female
- Gene Deletion
- Gene Targeting
- Genetic Loci -- genetics
- Hedgehog Proteins -- genetics
- Humans
- Intervertebral Disc -- diagnostic imaging
- Kyphosis -- congenital
- Lordosis -- congenital
- Lumbar Vertebrae -- diagnostic imaging
- MDS1 and EVI1 Complex Locus Protein
- Male
- Mice
- Mutation -- genetics
- Osteogenesis
- Proto-Oncogenes
- Receptor, Parathyroid Hormone, Type 1 -- genetics
- Spine -- abnormalities
- Tendons -- diagnostic imaging
- Thoracic Vertebrae -- diagnostic imaging
- Transcription Factors -- metabolism
- X-Ray Microtomography
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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