Dual mTORC1/2 inhibition in a preclinical xenograft tumor model of endometrial cancer. [electronic resource]
Producer: 20140411Description: 468-73 p. digitalISSN:- 1095-6859
- Animals
- Antineoplastic Combined Chemotherapy Protocols -- pharmacology
- Carboplatin -- administration & dosage
- Carcinoma, Endometrioid -- drug therapy
- Cell Growth Processes -- drug effects
- Cell Line, Tumor
- Endometrial Neoplasms -- drug therapy
- Everolimus
- Female
- Indoles -- pharmacology
- Mechanistic Target of Rapamycin Complex 1
- Mechanistic Target of Rapamycin Complex 2
- Mice
- Mice, Inbred BALB C
- Mice, Nude
- Multiprotein Complexes -- antagonists & inhibitors
- Protein Kinase Inhibitors -- pharmacology
- Proto-Oncogene Proteins c-akt -- antagonists & inhibitors
- Purines -- pharmacology
- Random Allocation
- Signal Transduction
- Sirolimus -- administration & dosage
- TOR Serine-Threonine Kinases -- antagonists & inhibitors
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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