Design, synthesis and evaluation of novel tacrine-rhein hybrids as multifunctional agents for the treatment of Alzheimer's disease. [electronic resource]
Producer: 20141006Description: 801-14 p. digitalISSN:- 1477-0539
- Alzheimer Disease -- drug therapy
- Amyloid beta-Peptides -- chemistry
- Animals
- Anthraquinones -- chemistry
- Chemistry Techniques, Synthetic
- Cholinesterase Inhibitors -- chemical synthesis
- Drug Design
- Kinetics
- Liver -- drug effects
- Metals -- chemistry
- Mice
- Molecular Docking Simulation
- Peptide Fragments -- chemistry
- Protein Multimerization -- drug effects
- Protein Structure, Secondary
- Tacrine -- chemical synthesis
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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