Plasma phosphorylated TDP-43 levels are elevated in patients with frontotemporal dementia carrying a C9orf72 repeat expansion or a GRN mutation. [electronic resource]
Producer: 20140620Description: 684-91 p. digitalISSN:- 1468-330X
- Aged
- Aged, 80 and over
- Blotting, Southern
- Brain -- metabolism
- C9orf72 Protein
- Case-Control Studies
- DNA Repeat Expansion
- DNA-Binding Proteins -- blood
- Enzyme-Linked Immunosorbent Assay
- Female
- Frontotemporal Dementia -- blood
- Humans
- Immunohistochemistry
- Intercellular Signaling Peptides and Proteins -- genetics
- Male
- Middle Aged
- Mutation
- Phosphorylation
- Progranulins
- Protein Precursors -- genetics
- Proteins -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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