Single-cell analysis of K562 cells: an imatinib-resistant subpopulation is adherent and has upregulated expression of BCR-ABL mRNA and protein. [electronic resource]
Producer: 20140513Description: 183-191.e5 p. digitalISSN:- 1873-2399
- Benzamides -- pharmacology
- Cell Adhesion -- drug effects
- Cell Survival -- drug effects
- Drug Resistance, Neoplasm -- drug effects
- Flow Cytometry
- Fusion Proteins, bcr-abl -- genetics
- Gene Expression Profiling
- Gene Expression Regulation, Neoplastic -- drug effects
- Humans
- Imatinib Mesylate
- In Situ Hybridization, Fluorescence
- K562 Cells
- Leukemia, Myelogenous, Chronic, BCR-ABL Positive -- genetics
- MicroRNAs -- genetics
- Phosphorylation -- drug effects
- Piperazines -- pharmacology
- Protein Kinase Inhibitors -- pharmacology
- Proto-Oncogene Proteins c-bcr -- genetics
- Pyrimidines -- pharmacology
- RNA, Messenger -- genetics
- Single-Cell Analysis -- methods
- Up-Regulation -- drug effects
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Publication Type: Journal Article
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