Allele-selective inhibition of expression of huntingtin and ataxin-3 by RNA duplexes containing unlocked nucleic acid substitutions. [electronic resource]
Producer: 20140307Description: 9329-38 p. digitalISSN:- 1520-4995
- Alleles
- Argonaute Proteins -- metabolism
- Ataxin-3
- Base Pair Mismatch
- Base Pairing
- Base Sequence
- Cell Line
- Drug Design
- Gene Silencing
- Humans
- Huntingtin Protein
- Hydrolysis
- Immunoprecipitation
- Kinetics
- Mutant Proteins -- antagonists & inhibitors
- Nerve Tissue Proteins -- antagonists & inhibitors
- Nuclear Proteins -- antagonists & inhibitors
- Oligonucleotides -- chemistry
- RNA, Messenger -- antagonists & inhibitors
- RNA, Small Interfering -- chemistry
- Recombinant Proteins -- biosynthesis
- Repressor Proteins -- antagonists & inhibitors
- Trinucleotide Repeats
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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