Development and implementation of a high-throughput compound screening assay for targeting disrupted ER calcium homeostasis in Alzheimer's disease. [electronic resource]
Producer: 20140826Description: e80645 p. digitalISSN:- 1932-6203
- Alzheimer Disease -- genetics
- Amyloid beta-Peptides -- metabolism
- Calcium -- metabolism
- Calcium Channels -- metabolism
- Carbachol -- pharmacology
- Cell Line
- Drug Discovery
- Endoplasmic Reticulum -- drug effects
- High-Throughput Screening Assays -- methods
- Homeostasis -- drug effects
- Humans
- Molecular Imaging -- methods
- Mutation
- Presenilin-1 -- genetics
- Presenilin-2 -- genetics
- Reproducibility of Results
- Small Molecule Libraries
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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